P-35: Anacyclus Pyrethrum and Tribulus Terrestris Simultaneously Improve The Sexual Parameters of Wistar Rats

Background: Propagation of race has been threatening by infertility which is a widespread impediment for human. About 50% of infertilities accounts for male Sexual dysfunction. Medicinal plants as a traditional treatment play a great role in remedies due to their accessibility, availability and affordability. Anacycluspyrethrum (AP) roots commonly known as pllitorybelongs. Tribulusterrestris (TT) (Zygophyllaceae) is a Mediterranean plant. Materials and Methods: 32 rats were divided into 4 groups: 1. PBS control group, 2. TT group, 3. AP group and 4. AT (AP and TT) group. They were treated for 25 days and their weight was recorded daily. After, they were anesthetized and sacrificed. Their testis was dissected for histological studies. Their sperms were isolated to measure sperm count, viability and motility. Serum was performed from their blood to carry out the rate of serum testosterone, LH and FSH and nitric oxide. Results: Body weight didn’t show significant increase in AT group compared to none of the groups as well as sexual organs weight. Sperm count, and motility of AT group significantly increased in AT group compared to control group. Viability showed a significant increase in AT group same results were obsessed in testosterone, LH, and FSH rates. NO increased significantly in this group compared to control group. Histological studies showed significant increase of spermatogonia, leydig, sertoli cell numbers and epithelial diameter in AP group compared to other groups as well as increased concentration of semeniferous spermatozoa. Conclusion: Significant increase of sperm viability, testosterone, LH, FSH compared to all other groups which were confirmed with histological studies by significant increase of spermatogonia, leydig, sertoli cell numbers and epithelial diameter in AP group compared to all other groups, as well as its efficacy in sperm count, viability and nitric oxide are all reasons for AP to be effectively ameliorative in MSD.